This example solves the Luo & Rudy 1994 model (more commonly known as the LR II or LRd model), defined by a CellML version of the model.

Please note: While this version of the model qualitatively compares well to the LR II paper for the action potential, the intracellular calcium dynamics have not been included correctly - namely there is no calcium-induced calcium-release (CICR) process in this version of the model. The original version of the model simulates CICR via a mechanism whereby CICR is induced if and only if the calcium accumulated in the cell in the 2 ms following (dV/dt)max exceeds a given threshold. This sort of process is a bit tricky to include in the CellML (or at least in a way that will work with the CellML abilitites of CMISS) so has been left out for now. I (Andre) don't see this as too much of a problem as the later LRd based models improve on this mechanism and their CellML implementations should be much better.

NOTE: This example requires a CellML 1.0 enabled version of CMISS to run.