\ Projects

The high level aim of the Wellcome Trust Heart Physiome Project is to integrate the various models of cardiac function that are being developed by the Oxford and Auckland research teams into a multi-scale modelling framework for the heart that can be used for addressing a wide range of scientific and clinical questions.
 
The multi-scale approach includes modelling structure-function relations at the levels of proteins, protein pathways, myocytes, myocardial tissue, the whole heart and the whole torso. The types of biophysical function being addressed include mechanics, electrophysiology, metabolism and blood flow, both ventricular and coronary. Underpinning the capturing of this functionality are a number of sub-projects as shown on left.